Akthelia has applied for a patent for a novel class of pharmaceutically active ingredients (APIs) that induce the expression of antibacterial peptides. These APIs are small molecules that activate production of the antibacterial peptides in cell and animal models. Efficacy has been shown against Shigella and Vibrio cholera infections in rabbits.
A clinical trial performed by a consortium involving Akthelia’s founders has been completed. The trial involved 288 participants and tested one of Akthelia’s actives in combination with traditional antibiotics. The results show that Akthelia’s APIs improved clinical score and other clinical markers of Tuberculosis over using the traditional antibiotics alone. The results have been published in PLOS One (http://www.ncbi.nlm.nih.gov/pubmed/26394045).
Akthelia is very proud to announce that Dr. Stefán Jökull Sveinsson has joined Akthelia’s board of directors. Dr. Sveinsson was Executive Vice President-Research & Development at Actavis for over 15 years where he directed drug development. Prior to that, he directed drug development at Delta and was a professor in Pharmacology at the University of Iceland. After leaving Actavis he has worked as an independent advisor in the pharmaceutical industry.
Jón Ingi Benediktsson has joined Akthelia as General Manager. Jón Ingi has extensive experience in biotech investments. He was the CEO of Líftæknisjóðurinn (MP Bio) from November 2000 – April 2005, then he served as Director for the Akureyri University Research and Innovation Center. From January 2008 he was member of SEED Capital, the largest early stage venture fund in Denmark, life science investment team as Investment Manager and later on as Investment Director, responsible for their overall early stage life science investments. Akthelia is looking forward to having him on board.